The astringent and calm quality of his deep voice has landed him many roles in films, dubbing, animation, and video games. He is most known for the roles of Spawn (Soulcalibur II), Black Jack(Black Jack), Solid Snake, Naked Snake, Solidus Snake and Venom Snake (Metal Gear games), Gamigami Devil (Popolocrois), Shunsui Kyouraku (Bleach), Lieutenant Garuru (Sgt. Frog), Gwendel von Voltaire (Kyo Kara Maoh!), Batou (Ghost in the Shell series and movies), Blackbeard (One Piece), Twin brother police Inspector's Sango and Jugo Yokomizo (Detective Conan), Bryan Hawk (Hajime no Ippo), All For One (My Hero Academia), Rider (Fate/Zero), Wamuu (JoJo's Bizarre Adventure), Anavel Gato(Mobile Suit Gundam 0083: Stardust Memory) and the various incarnations of Xehanort (Kingdom Hearts series). Apart from voicing villainous or jokester characters, he also occasionally does narration for anime shows. He is the son of voice actor Chikao Ohtsuka.